Spa shots often use low-grade compounds and skip medical evaluation risking imbalance or ineffective results, or even missing important diagnosis of underlying medical conditions
Therefore, gradual dose escalation strategies prove beneficial for enhancing tolerability and treatment adherence
Patients should be informed about the expected side effect profile before initiating therapy
Sterne J, Savovi J, Page M, Elbers R, Blencowe N, Boutron I, et al
In vitro , in comparison with control, healthy animals, the assessment of splenic cells (day 21) demonstrated that the 6-methylprednisolone animals had declined reactivity to nitrogen, while the addition of BPC 157 (1 g/g cream) returned cell reactivity to normal values (Mikus et al., 2001